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Kajal Khomane
Kajal Khomane

Subcutaneous Nucleic Acid

Subcutaneous nucleic acid therapeutics are medicines made from DNA- or RNA-based molecules that are administered by subcutaneous (under-the-skin) injection. These therapies are designed to modify gene expression or protein production to treat a variety of diseases.

Types of nucleic acid therapeutics

  • Antisense oligonucleotides (ASOs) – Short synthetic strands of nucleic acids that bind to RNA to alter gene expression.

  • Small interfering RNA (siRNA) – Uses the RNA interference pathway to reduce production of specific proteins.


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